Developing context-specific next-generation sequencing policy

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Strategies and Clinical Applications of Next Generation Sequencing

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Abstract DNA sequencing is one of the great valuable techniques in molecular biology, which can be used to detect the sequence of nucleotides in a DNA fragment. The high-throughput se­quencing known as Next Generation Sequencing (NGS) revolutionized genomic research and molecular biology; therefore, the whole human genome can be sequenced with a low cost in several days. NGS technology is simi...

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Next-generation sequencing (NGS), otherwise known as deep or massively parallel sequencing, refers to the technological advances in DNA sequencing instrumentation that enable the generation of hundreds of thousands to millions of sequence reads per run. Sequencing of the human genome, which was once a >10-year endeavor by the NIH at the cost of approximately $3 billion (1), can now be done rout...

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1Human Genetics Center, The University of Texas School of Public Health, Houston, TX 77025, USA 2Departments of Biomedical Informatics and Psychiatry and Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University Medical Center, Nashville, TN 37232, USA 3Department of Genetics, The University of Georgia, Life Sciences Building, Athens, GA 30602, USA 4Human Genome Sequencing Center, Baylor Co...

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ژورنال

عنوان ژورنال: Nature Biotechnology

سال: 2016

ISSN: 1087-0156,1546-1696

DOI: 10.1038/nbt.3545